AFAmazonS3Manager *s3Manager = [[AFAmazonS3Manager alloc] initWithAccessKeyID:@"..." secret:@"..."];
s3manager.requestSerializer.region = AFAmazonS3USWest1Region;
s3manager.requestSerializer.bucket = @"my-bucket-name";

NSString *destinationPath = @"/pathOnS3/to/file.txt";

[s3Manager postObjectWithFile:@"/path/to/file.txt"
              destinationPath:destinationPath
                   parameters:nil
                     progress:^(NSUInteger bytesWritten, long long totalBytesWritten, long long totalBytesExpectedToWrite) {
                        NSLog(@"%f%% Uploaded", (totalBytesWritten / (totalBytesExpectedToWrite * 1.0f) * 100));
}
                      success:^(id responseObject) {
                        NSURL *resultURL = [s3manager.requestSerializer.endpointURL URLByAppendingPathComponent:destinationPath];
                        NSLog(@"Upload Complete: %@", resultURL);
}
                      failure:^(NSError *error) {
                         NSLog(@"Error: %@", error);
}];